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临床试验/NCT07012083
NCT07012083已完成不适用

Egyptian Doctors' Adherence to Anti-rabies Post-exposure Prophylactic Protocols; A Survey Study

Tanta University1 个研究点 分布在 1 个国家目标入组 214 人开始时间: 2025年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
214
试验地点
1
主要终点
Adherence to Anti-rabies PEP Guidelines

研究概览

简要总结

This study aims to investigate physicians' adherence to Advisory Committee on Immunization Practices (ACIP) guidelines regarding Anti-rabies post-exposure prophylaxis in Egypt.

详细描述

There is no known effective treatment for rabies, and virtually all cases are fatal. Although the prognosis is poor in patients who develop rabies, the disease is usually preventable with proper wound care and post-exposure prophylaxis. Following a thorough risk assessment, the decision to initiate rabies post-exposure prophylaxis should be made. The risk assessment should consider the type of exposure, local rabies epidemiology in animals, vaccination history of the animal, circumstances of the exposure incident, and the availability of the animal for observation or rabies testing .

The World Health Organization (WHO) and the Advisory Committee on Immunization Practices (ACIP) have adopted guidelines for starting post-exposure prophylaxis (PEP) against rabies. The decision to start Anti-Rabies PEP is usually made in primary health care units or emergency departments .

Lack of adherence to these guidelines might result in unnecessary costs and medical risks, such as injection site reactions and systemic hypersensitivity reactions . This malpractice of inappropriate anti-rabies PEP prescription is not uncommon.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Physicians who treat patients with animal bites potentially requiring post-exposure anti-rabies prophylaxis. The sample will include emergency physicians, general practice or family physicians, and surgeons of both sexes, with varying degrees of experience and post-graduate clinical training.

排除标准

  • •Incomplete record filling

结局指标

主要结局

Adherence to Anti-rabies PEP Guidelines

时间窗: 6 months

This study aims to investigate physicians' adherence to the Advisory Committee on Immunization. Practices (ACIP) guidelines regarding Anti-rabies post-exposure prophylaxis in Egypt. This will be through a score given for the correct response to the case-based questionnaire. This questionnaire include 10 case-based scenarios where anti-rabies post-exposure prophylaxis may or may not be indicated as per ACIP guidelines. True response will be scored 1, wrong response will be scored 0 with maximum total score of 10. Higher score reflects better adherence to guidelines recommendations \& vice versa.

次要结局

  • Health & Economic burden of such malpractice(9 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Ezzat Nasreddin

Lecturer of Emergency Medicine

Tanta University

研究点 (1)

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