Incidence of Acute Kidney Injury After Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The incidence of AKI following a laparoscopic cholecystectomy
研究概览
简要总结
The aim of this study is to establish AKI incidence in patients who are undergoing laparoscopic cholecystectomy and to identify the potential risk factors associated with the development of AKI.
详细描述
Introduction: Laparoscopic procedure produces adverse effects on splanchnic organs. Pneumoperitoneum is a non-physiologic condition that causes a higher intra-abdominal pressure (IAP) and is associated with significant direct and indirect effects on renal physiology.
Aim of the study:
To establish AKI incidence in patients who are undergoing laparoscopic cholecystectomy.
To identify the potential risk factors associated with the development of AKI. To establish the relationship between the IAP during the procedure and the AKI incidence.
Study Design:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age > 18 years, able to sign the consent form, stable kidney function.
排除标准
- •end stage renal disease
- •acute kidney injury or need of dialysis three months prior the procedure
- •acute infection
- •acute inflammation
- •malignancy
- •pregnancy
结局指标
主要结局
The incidence of AKI following a laparoscopic cholecystectomy
时间窗: Up to one week after the procedure
kidney function, included estimated GFR and urinary markers will be measured
次要结局
未报告次要终点
研究者
Khaled Khazim, MD
Nephrology specialist
Western Galilee Hospital-Nahariya