Clinical Respiratory Investigation in Post Covid-19 Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Characteristics of lung
研究概览
简要总结
To evaluate pulmonary changes and the results of a cardiopulmonary rehabilitation protocol (CPRP) in patients after SARS-VOC-2 infection. Clinical trial type study to be conducted between 2020 and 2024 involving clinical-functional cardiopulmonary imaging and blood transcriptome profile: before CPRP (T1), 2 months after CPRP (T2) and 1 year later (T3). Expected results: a) clinical, image and transcriptome changes; b) clinical-functional improvement after CPRP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •With confirmed diagnosis for SARS-COV-2.
排除标准
- •With any type of simultaneous pneumopathy.
- •Patients with autoimmune disease
- •People with simultaneous infectious diseases
- •Pregnant women
- •With degenerative diseases of the nervous system or musculoskeletal system
结局指标
主要结局
Characteristics of lung
时间窗: post treatment in 3 days
In the supine position, the patient will perform deep inspiration followed by momentary apnea inside the high resolution scanner to capture cross-sectional images of the chest with smaller cuts than 1mm of collimation which helped in the detection of even small lesions.
Respiratory muscle strength
时间窗: post treatment in 3 days
Respiratory muscle strength will be assessed using the digital manovacuometer. The measurement will be performed as follows the patient will be asked to empty the lungs to the residual volume and then perform an inhalation until the total lung capacity.
次要结局
未报告次要终点
研究者
Rodrigo Santiago Barbosa Rocha, Phd
Director of Human Movement Department
Universidade Metodista de Piracicaba