A randomised controlled trial comparing the efficacy of conventional absorbable sutures and knotless absorbable sutures using a split-mouth design.

igel Tan0 个研究点目标入组 70 人开始时间: 2021年4月9日最近更新: 2022年4月19日

试验速览

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•1.Patients referred for third molar removal from a primary care provider
•2.Patients who volunteer participation
•3.Patients may be either male or female
•4.The patient has been screened by the primary investigator or supervising specialist for suitability to participate in the study
•5.Are aged between 18 and 44 years
•6.Are able to understand verbal and written instructions.
•7.Present with bilateral similarly impacted mandibular third molars as determined using Winter’s (1926) classification system , requiring surgical removal
•8.Are able to tolerate outpatient oral surgery under local anaesthetic and intravenous sedation
•9.ASA l or ll
•10.The patient has provided informed consent regarding:
•a.Participation in the study
•i.The use of knotless sutures in the closure of the surgical wound
•b.Surgical removal of third molars under local anaesthetic and intravenous sedation

•1.American society of anaesthesiologists (ASA) physical classification III or IV
•2.Polypharmacy (greater than or equal to 5) medications
•4.Patients contraindicated to undergo surgical third molar removal
•5.Patients contraindicated to treatment under monoagent midazolam IV sedation
•6.Opioid and illict drug addiction
•7.Patients that have allergies or contraindications to the procedural usage of:
•a.midazolam
•b.dexamethasone
•c.parecoxib
•d.paracetamol
•e.ibuprofen
•f.co-amoxiclav
•g.cefazolin
•h.clindamycin
•i.chlorhexidine
•8.The presence of symptomatic pericoronitis.
•9.The presence of other pathology in the oral cavity.
•10.Patients with poor oral hygiene (plaque >1/3 of tooth surface).
•11.Pregnant or lactating women.
•12.Male patients who do not agree to facial hair removal.
•13.Patients who are unable to give informed consent.
•14.Patients who decline participation.
•15.Patients who are unable to attend the required follow-up appointments.
•16.Patients who are unable to comprehend directions and instructions.
•17.Patients unwilling to trim facial hair for the purposes for the measurement of facial swelling

发起方

igel Tan