Ventilator Mode and Respiratory Physiology
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Excess tidal volume
研究概览
简要总结
Modern intensive care units (ICUs) are increasingly adopting newer modes of mechanical ventilation such as adaptive pressure control (APC) modes but there are limited data available regarding risks and benefits of newer modes versus traditional ventilation modes. APC can inadvertently deliver high tidal volumes, which maybe harmful. High tidal volumes may be unrecognized by the provider, due to the complexities of ventilator algorithms and patient interactions. The objective of this aim is to identify risk factors for excess tidal volumes in patients on adaptive pressure control.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Admitted to ICU with acute respiratory failure
- •On adaptive pressure control mode of ventilation
- •Tidal volumes set between 5-8 cc/kg ideal body weight
排除标准
- •Current use of neuromuscular blockade
- •Inability to obtain consent from patient or surrogate decision maker
- •Treating clinician refusal
结局指标
主要结局
Excess tidal volume
时间窗: From enrollment to end of monitoring at 4 hours
Exhaled tidal volume greater than 2cc/kg ideal body weight above intended or set tidal volume
次要结局
未报告次要终点
研究者
Alex Pearce
Principal Investigator
University of California, San Diego