Ultrasound-guided Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Appendectomy: A Prospective, Randomized, Controlled Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 168
- 试验地点
- 2
- 主要终点
- Postoperative 24-hours total tramadol hydrochloride consumption
研究概览
简要总结
Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.
详细描述
168 patients (ASA I-II-III) between 18 and 65 years of age, who were to undergo laparoscopic appendectomy, were randomized and divided into two groups. 32 patients were dropout for different reasons.(68 patients in each of the TAP block and QLB block groups). TAP block was performed for TAP group and QLB block was performed for QLB group. Postoperative analgesia was provided by intravenous tramadol hydrochloride using a patient-controlled analgesia device. 24-hour total tramadol hydrochloride consumption was primary outcome measure.Postoperative numeric rating scale values were the secondary outcome measure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages of 18-65
- •Patients who will undergo laparoscopic appendectomy
- •ASA I-II-III patients
排除标准
- •Clinically known local anesthetic allergy
- •Morbid obesity (body mass index>40 kg m2)
- •Clinically diagnosis of opioid, alcohol and substance dependence
- •Clinically diagnosis of psychiatric disease
- •Coagulopathy
- •Patients with ASA IV-V
结局指标
主要结局
Postoperative 24-hours total tramadol hydrochloride consumption
时间窗: 24 hours postoperatively
This will be measured by pca device in the 24 hour after
次要结局
- Numerical rating scale (NRS) scores of patients(24 hours postoperatively)
研究者
Gokhan Sertcakacilar, MD
Principal investigator
Bakirkoy Dr. Sadi Konuk Research and Training Hospital