To study incidence and evolution of cardiovascular changes in Mucor mycosis infection at a tertiary care centre in North India
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Total cardiovascular events in the group
研究概览
简要总结
Mucormycosis is an invasive fungal infection . In immunocompromised patients they cause vascular invasion and infarction of organs. Cardiac involvement in the form of myocarditis, angio invasive mucormycosis causing acute coronary syndrome has been reported. We planned an observational study to find out incidence and range of cardiovascular involvement in mucormycosis patients. We take both retrospective and prospective data. We do baseline ECG , echocardiography , cardiac biomarkers and follow them up for 3 months post hospitalisation. We look for any cardiovascular involvement , acute coronary syndrome , arrhythmias during hospitalisation and follow up.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •age greater than 18 years nucor cases reporting to cardiology out patient department valid informed consent.
排除标准
- •not giving consent.
结局指标
主要结局
Total cardiovascular events in the group
时间窗: 4 weeks after presentation
次要结局
- Incidence of acute myocardial events in Mucormycosis population 
at baseline and during hospital stay(30 days)
- Myocarditis or myocardial infarction or stenosis detected with ST segment elevation or depression associated with troponin elevation and echocardiography(30 days post hospital admission)
- Characterization of inflammation on cardio-vascular outcomes(30 days post hospital admission)
- New onset cardiac arrhythmia(30 days post hospital admission)
