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临床试验/NL-OMON33044
NL-OMON33044已完成不适用

A randomised controlled trial comparing in vitro maturation of oocytes with in vitro fertilisation in women with an increased risk of ovarian hyperstimulation syndrome. - IVM

Jeroen Bosch Ziekenhuis0 个研究点目标入组 450 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
450

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • - Women with PCOS according to the Rotterdam Criteria (The Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group, 2004) which not did achieve an ongoing pregnancy after ovulation induction (with clomiphene citrate or LEO and rFSH)
  • - Women with an IVF or ICSI indication and increased risk for developing OHSS (history of OHSS or cycle cancellation for imminent OHSS)

排除标准

  • - Woman or partner younger than 18 years and woman older than 38 years
  • - Unable to speak or read the Dutch language
  • - Medical contraindication for pregnancy or childbirth
  • - Positive serology for Hepatitis B, C or HIV (conform: Standpunt inzake screening op infectieziekten bij kunstmatig geassisteerde voortplanting, www.embryologen.nl).
  • - Diminished ovarian reserve: early follicular serum FSH > 10 IU/l and/or poor response during earlier COH/IVF or COH/ICSI with ³ 150 IU rFSH/day (definition poor response: cycle cancellation in growth of < 4 follicles or < 3 oocytes after oocyte retrieval) (Bancsi 2002).
  • - Persisting ovarian cysts > 30 mm diameter.

研究者

发起方
Jeroen Bosch Ziekenhuis

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