Expiratory flow limitation and heliox breathing in resting and exercising chronic obstructive pulmonary disease (COPD) patients: a randomised double-blind cross-over trial

niversity of Milan (Univrsità degli Studi di Milano) (Italy)0 个研究点目标入组 26 人开始时间: 2009年6月3日最近更新: 2019年7月29日

试验速览

•1. Stable COPD patients with stable airway obstruction with any level of forced expiratory volume in one second (FEV1) value expressed of predicted
•2. Male or female patients, 40 years of age or older
•3. Patients must be current or ex-smokers with a smoking history of more than 10 pack years
•4. Patients must be to able to perform technical acceptable pulmonary function tests and must be able to perform an incremental exercise test on a cycle ergometer

•1. Patients with a signficant disease other than COPD that conditioning a risk for exercise testing (this is evaluated by medical investigators)
•2. Patients with a history of asthma
•3. Patients with a diagnosis of paroxysmal tachycardia, atrial fibrillation and recent history of myocardial infarction (less of 2 years)
•4. Known active tubercolosis
•5. History of cystic fibrosis
•6. Pregnant women
•7. Patients aged more than 85 years old

发起方

niversity of Milan (Univrsità degli Studi di Milano) (Italy)