Pericapsular Nerve Group Block: An Imaging Study for Determination of the Spread of the Injectate Using 3-D CT Scan
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Concentration of the local anesthetic reaching specific anatomical areas of interest around the hip joint
研究概览
简要总结
Over the last 20 years, different interventional regional analgesia techniques have been proposed to treat pain after hip surgeries.
The most commonly used techniques are the fascia iliaca and femoral nerve blocks, resulting in reduced pain scores, opioid-sparing effects, and opioid-related adverse effects. However, these interventional analgesia techniques result in a motor block and muscle weakness of the quadriceps muscle, impeding early ambulation and rehabilitation.
Recently, the pericapsular nerve group (PENG) block has been proposed as an effective choice for analgesia after hip surgeries while sparing the motor function of the lower extremities. The aim of this technique is to inject local anesthetic to target the more distal sensory branches innervating the anterior aspect of the hip joint.
详细描述
Ten patients scheduled for hip surgery were included after Ethical Committee approval and informed consent were obtained.
Preoperatively, patients received an ultrasound-guided pericapsular nerve group block. The injections were performed preoperatively using a Canon US Applio 700 with a linear transducer (14 to 6 MHz), and a 21-gauge, 80 mm stimulating needle (SonoPlex Stim, Pajunk ® ️ GmbH, Germany). After confirmation of the correct needle tip position with 2 mL of sodium chloride 0.9%, 20 mL of injectate containing 18 mL ropivacaine 0.5% with 2 mL of radiopaque contrast (Iomeron 300: 61.24% w/v of Iomeprol equivalent to 30% iodine or 300 mg iodine/mL (Bracco UK Limited)) was injected.
After surgery, high-definition CT scans (Siemens) were obtained to determine the distribution patterns of the injectates.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
盲法说明
No masking was required for this study.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •an indication for PENG blocks for postoperative pain management
- •American Society of Anesthesiologists (ASA) physical status I or II
- •at least 18 years old, and able to understand the purpose and risks of the study
排除标准
- •body mass index above 35 kg/m2
- •hepatic or renal insufficiency
- •history of allergic or adverse reactions to local anesthetics or contrast agents.
研究组 & 干预措施
Pericapsular nerve group block group
All subjects enrolled in the study received a pericapsular nerve group block using a local anesthetic mixed with a contrast agent. After injection, subjects were transferred to the CT scan to obtain a 3D reconstruction to determine the spread of the injectate.
干预措施: Pericapsular nerve group block (Procedure)
Pericapsular nerve group block group
All subjects enrolled in the study received a pericapsular nerve group block using a local anesthetic mixed with a contrast agent. After injection, subjects were transferred to the CT scan to obtain a 3D reconstruction to determine the spread of the injectate.
干预措施: 18 mL ropivacaine 0.5% + 2 mL radiopaque contrast (Drug)
结局指标
主要结局
Concentration of the local anesthetic reaching specific anatomical areas of interest around the hip joint
时间窗: 2 hours
Computed tomography images will be used as measurement tool
次要结局
未报告次要终点
研究者
Philippe Gauthier
Principal Investigator
Centre Hospitalier Universitaire de Liege