A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Femoral Nerve Block for Analgesia Post Total Knee Arthroplasty
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Morphine consumption
研究概览
简要总结
Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages. It is a painful surgery and one of the methods to reduce post-operative pain is performing a regional anaesthesia technique. The current practice is to perform a femoral nerve block (FNB) which blocks the nerves supplying the knee joint and the thigh muscles (quadriceps). This provides effective analgesia. However, it also results in weakness of the quadriceps and may result in falls post-operatively.
Adductor canal block (ACB) is a new, alternative regional anaesthesia technique which is hypothesised to provide as effective analgesia, with less quadriceps weakness compared to FNB, hence potentially reducing the risk of falls post-operatively.
Investigators aim to study if the analgesia provided by ACB is as good as FNB while preserving quadriceps strength.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ages 45-85
- •American Society of Anaesthesiologists physical status 1-3
- •BMI 18-35 kg/m2
排除标准
- •inability to give consent, communicate, cooperate
- •Patients with regular consumption of strong opioids (morphine, oxycodone) or steroids
- •Patients with allergy to local anaesthetics or any drugs included in the study
- •Patients with lower limb surgery in the preceding year
- •Patients with pre-existing neurological deficits
- •Patients who are unsuitable for general anaesthetics (eg difficult airway)
研究组 & 干预措施
Femoral Nerve Block
Femoral Nerve block performed with 0.5% Ropivacaine 30mls (150mg)
干预措施: Ropivacaine (Drug)
Adductor Canal block
Adductor Canal block performed with 0.5% Ropivacaine 30mls (150mg)
干预措施: Ropivacaine (Drug)
结局指标
主要结局
Morphine consumption
时间窗: first 24 hours
次要结局
- Quadriceps strength, ability to mobilise(24, 48 hours)
- Side effects of opioids- sedation, nausea and vomiting(48 hours)
- Morphine consumption(48 hours)
- Pain scores(1, 6, 12, 24, 48)