Huizhou Mother-infant Cohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 5,216
- 试验地点
- 1
- 主要终点
- Children weight changes.
研究概览
简要总结
The Huizhou mother-infant cohort was set up to investigate the effect of dietary factors and environmental exposures during pregnancy on health consequences of mothers and offsprings in Huizhou, China.
详细描述
Huizhou mother-infant cohort (No-worry Baby Project) is a scientific research/public health project jointly initiated by Huizhou First Maternity and Child Healthcare Hospital and School of Public Health, Sun Yat-sen University. The project plans to recruit 10,000 participants since early pregnancy and follow up for three years after birth in the first stage. Biological samples, data from questionnaires survey and clinical information will be collected for both mothers and infants. The study is aimed to investigate the effects of dietary factors and environmental exposures during pregnancy on infants' health as well as the prognosis of diseased mothers. The study will have essentially both clinical and public health implications to find effective strategies for prevention and management of a range of chronic disorders (above mentioned) during pregnancy and exploration of the possible impacts on offspring health. The cohort will provide scientific basic for improvement of mother and infant's health.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant women who have plan to delivery and participate in child care in Huizhou hospital;
- •Pregnant women who have resided in Huizhou for at least 3 years;
- •Pregnant women who are consent for specimens and data collection and follow-ups for both mother and infant.
排除标准
- •Pregnant women who are with gestational age more than 24 weeks ;
- •Pregnant women who refuse to participate or be unwilling to sign informed consent;
- •Pregnant women who are mentally incapacitated and need guardians.
结局指标
主要结局
Children weight changes.
时间窗: At age of 1 month, 3 months, 6months, 1 year, and 3 year.
Weight is measured in kilograms.
Children height changes.
时间窗: At age of 1 month, 3 months, 6months, 1 year, and 3 year.
Height is measured in meters.
Number of participant with gestational complications.
时间窗: At delivery.
Including gestational hypertension and preeclampsia, and gestational diabetes mellitus.
Number of adverse birth outcomes.
时间窗: At delivery.
Including dystocia,stillbirth, fetal macrosomia and child with birth defect.
次要结局
- Maternal weight changes(kg).(At 20 weeks of gestation, 28 weeks of gestation, the time before labor and 30 days after delivery.)
- Number of participant with postnatal depression.(At 30 days after delivery.)
研究者
LIU ZHAOMIN
Professor in Department of Nutrition and Food Hygiene
Sun Yat-sen University