COGNITIVE FUNCTIONS AND ITS CORRELATION WITH INTERFERON - GAMMA AND SEMAPHORIN 4D LEVELS IN DEPRESSED PATIENTS TREATED WITHPAROXETINE CR / BUPROPION SR: A PILOT STUDY - Cognitive functions and its correlation with Interferon-gamma and Semaphorin 4D levels in depressed patients treated with Paroxetine CR / Bupropion SR: A pilot study

CMS and GTB Hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

研究概览

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•1. Patients of either sex with age between 18 -60 years.
•2. Patient must meet DSM-5 (fifth edition of diagnostic and statistical manual of mental disorders) criteria MDD (single or recurrent episode).
•3. Patient Health Questionnaire (PHQ-9) score of at least 15 at screening.
•4. Patients/guardian willing to give written informed consent.

•1. Patients of acute suicidal risk.
•2. Lifetime DSM-5 diagnosis of dementia, schizophrenia, schizoaffective or bipolar diseases, post-traumatic disorder, obsessive compulsive disorder, anxiety, eating disorder.
•3. Substance dependency.
•4. Depression due to organic brain disease.
•5. Pregnant and lactating women.
•6. Any significant medical illness (hypertension, diabetes, epilepsy, asthma chronic kidney disease, hypothyroidism).
•7. Patients/guardian not willing to give informed consent

发起方

CMS and GTB Hospital