Comparison of Intrathecal Fentanyl or Sufentanil in 1 mg Bupivacaine Spinal Anesthesia for TURP in Elderly Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- time to achieve peak sensory block without unimpaired motor strength
研究概览
简要总结
Adequate sensory block for surgical procedure without side effects and immediate mobilization after surgery are desirable anesthetic technique in various surgeries. Considering the sensory innervations to the prostate, a sensory block up to L1 - T12 is adequate to the TURP. Low-dose intrathecal local anesthetics may meet these criteria, but occasional lack of sufficient sensory block could be troublesome. In this randomized study, the investigators evaluated the spinal anesthetic characteristics following intrathecal administration of bupivacaine 1 mg with fentanyl or sufentanil in elderly patients undergoing TURP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •age over 65 ~ under 85yrears old
- •elderly patients undergoing TURP
- •only spinal anesthesia
- •patients consent about this study
排除标准
- •spine surgery History
- •coagulopathy
- •impaired communication
- •impaired orientation
- •DM complication neuropathy
- •BMI > 30 -> overweight patients.
研究组 & 干预措施
group A
Fentanyl
干预措施: Fentanyl (Drug)
Group B
Sufentanil
干预措施: Sufentanil (Drug)
结局指标
主要结局
time to achieve peak sensory block without unimpaired motor strength
时间窗: 2 minites after injection intrathecally start
peak sensory \& sympathetic block level, time to peak sensory \& sympathetic block level, motor block level at peak sensory \& sympathetic block level, lowest BP and HR during spinal anestheisa, frequency of painkiller
次要结局
未报告次要终点