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临床试验/NCT03663439
NCT03663439Unknown不适用

Evaluation of Modified Shell Technique Versus Onlay Bone Graft for Reconstruction of Atrophic Anterior Maxilla

Cairo University0 个研究点目标入组 14 人开始时间: 2018年9月16日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
14
主要终点
Histomorphometric

研究概览

简要总结

Amount of bone volume and (width and height):

Will be measured using linear measurements from CBCT after 6 month from implant insertion.

Will be measured using Histometric analysis of bone area percent sampling from recipient site after 6 months.

详细描述

Augmentation of insufficient bone volume can be brought about by different methods, including, particulate and block grafting materials, Guided Bone Regeneration with or without growth and differentiation factors, ridge splitting, expansion and distraction osteogenesis, either alone or in combination. These techniques may be used for horizontal/vertical ridge augmentation

Autograft is considered as the Gold Standard for bone transplantation and various studies have shown efficacy for it. It is osteogenic, osteoconductive and osteoinductive. Autografts can be derived from extra oral source (iliac crest, ribs) or intraoral source (chin, ramus). They can be used in block or particulate form. Corticocancellous block grafts are preferred because of enhanced revascularization of the cancellous portion, and mechanical support and rigidity of the cortical portion, which ensures optimal ridge augmentation.

Fouad Khoury presented a three-dimensional (3D) reconstruction technique for atrophic ridges and complicated vertical bone defects using mandibular bone block graft "the Gold standard". There are several possibilities for augmentation of bone volume depending on situation, indication and adequate diagnosis; the treatment options can be extended from minimally invasive procedures with locally harvested bone grafts in local anesthesia, to very sophisticated grafting techniques for 3D bone reconstruction with extra oral harvested bone grafts. Khoury reported that his ascending ramus grafts is almost 5 times more than chin grafts

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

盲法说明

control group (modified shell technique) study group (onlay bone graft)

入排标准

性别
All
接受健康志愿者

入选标准

  • patients with atrophic anterior maxilla
  • No intraoral soft and hard tissue pathology
  • No systemic condition that contraindicate implant placement
  • Both sexes.

排除标准

  • Heavy smokers more than 20 cigarettes per day.
  • Patients with systemic disease that may affect normal healing.
  • Psychiatric problems
  • Immunodeficiency pathology, bruxism, stress situation (socially or professionally), emotional instability, and unrealistic aesthetic demands.

研究组 & 干预措施

modified shell technique

Experimental

block of bone from the mandibular ramus divided into two shells ,grafting one shell in the anterior maxilla to increase width

干预措施: modified shell technique (Procedure)

onlay bone graft

Active Comparator

grafting block of bone from the mandibular ramus in the atrophic anterior maxilla

干预措施: modified shell technique (Procedure)

结局指标

主要结局

Histomorphometric

时间窗: 3 months

Type of bone formed by graft, after 3 months biopsy from the bone formed

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amr hisham mohamed

Dentist

Cairo University

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