NCT01237145已完成不适用
Study to Determine the Immune Response From Broncho-alveolar Cells Against Pigeon Specific Antigens
Bossink, A.W.J.1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2011年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- ELISPOT response in cells obtained from broncho-alveolar lavage
研究概览
简要总结
The purpose of this study is to establish if cells present in lung tissue during extrinsic allergic alveolitis (EAA) are able to elicit an immune response against specific antigens. The hypothesis is: cells in BAL lavage fluid from patients with EAA will be responsive to specific antigens and this response can be measured using ELISPOT.
详细描述
Subjects suffering from extrinsic allergic alveolitis caused by pigeons will undergo a broncho alveolar lavage. Cells obtained from this BAL will be used for ELISPOT technique with pigeon specific antigens
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •suspicion of pigeon induced extrinsic alveolitis
排除标准
- •use of oral steroids
- •unable to give informed consent
- •age below 18
结局指标
主要结局
ELISPOT response in cells obtained from broncho-alveolar lavage
时间窗: 2 days
All elispots will be performed the same day, the end point will be available the next day
次要结局
- Elispot response in cells from blood(2 days)
研究者
A.W.J.Bossink
Dr
Bossink, A.W.J.
研究点 (1)
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