Clinical efficacy of Ding's manipulation in the treatment of knee osteoarthritis and its mechanism based on NF- kappa B signaling pathway

Shanghai University of Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. Repeated knee joint pain in the past month;
•2. X-ray films (standing position or load-bearing position) showed narrowing of joint space, subcartilage osteosclerosis and / or cystic degeneration, and formation of osteophyte at the edge of the joint;
•3. Aged = 50 years old;
•4. Morning stiffness time = 30 min;
•5. There is bone friction sound (feeling) during the activity.

•1. There is skin damage around the knee joint;
•2. Patients with history of knee surgery and severe trauma;
•3. Patients with secondary OA, complicated with rheumatoid arthritis, gouty arthritis, infectious arthritis and other joint diseases;
•4. Patients with diabetes, systemic infection, severe abnormal liver and kidney function, malignant tumor and other diseases;
•5. Patients received NSAIDs, intra-articular injection and other related treatment in the past 3 months;
•6. Those who are allergic to the drugs in this study;
•7. Pregnant or lactating women;
•8. Mental disorder or cognitive dysfunction;
•9. Those who did not accept or could not adhere to the treatment plan of this study.

发起方

Shanghai University of Chinese Medicine