跳至主要内容
临床试验/NCT06192199
NCT06192199已完成不适用

The Diagnostic Value of APTT/Fibrinogen Ratio in Pulmonary Embolism

Nanfang Hospital, Southern Medical University1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2018年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,000
试验地点
1
主要终点
Cutoff value of APTT/FIB between patients with and without acute pulmonary embolism

研究概览

简要总结

From January 1, 2023 to December 30, 2023, patients who were suspected of pulmonary embolism and underwent CTPA examination at Nanyang Hospital of Southern Medical University were divided into pulmonary embolism group and non pulmonary embolism group. 1. Collect relevant data, including gender, age, primary disease, CTPA imaging and reports, BNP, troponin, electrocardiogram, cardiac ultrasound, PT, APTT, TT, fibrinogen, D-dimer, etc., and analyze demographic data, pulmonary embolism risk grading, APTT/fibrinogen ratio, and determine their cut-off values through statistical analysis of the two groups. 2. Follow up on the APTT/fibrinogen ratio after anticoagulation treatment and bleeding in the pulmonary embolism group.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Voluntary signing of informed consent form;
  • When signing the informed consent form, the age is equal to or greater than 18 years old, regardless of gender;
  • From January 1, 2023 to December 30, 2023, the patient was diagnosed with suspected pulmonary embolism at the Southern Hospital of Southern Medical University and underwent enhanced pulmonary artery scanning examination.

排除标准

  • Patients with gastrointestinal bleeding, severe trauma, acute coronary syndrome, severe liver disease (childC grade), and coagulation dysfunction;
  • Patients with pulmonary embolism diagnosed outside the hospital and regular anticoagulation;
  • Patients undergoing regular anticoagulant therapy such as atrial fibrillation and valve replacement;
  • Patients deemed unsuitable for participation in this study by the researchers.

结局指标

主要结局

Cutoff value of APTT/FIB between patients with and without acute pulmonary embolism

时间窗: 2024.01-2026.12

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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