The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 165
- 试验地点
- 1
- 主要终点
- Rate of Antibiotic-Associated Diarrhea
研究概览
简要总结
The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
详细描述
The participants will be children aged 3 months to 3 years.The zinc group received oral zinc supplementation; 2.5 ml every 12 hours for children aged <1 year and 5 ml every 12 hours for older children; the probiotics group received oral probiotics; 1 probiotic sachet; and the control group received nothing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 3 Months 至 3 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •children aged 3 months to 3 years
- •prescribed antibiotics for various medical conditions
排除标准
- •Diarrhea, Dysentery
- •Underlying chronic disease
研究组 & 干预措施
65 children in cotrol group
Only standard medication.
65 children in Zinc group
The zinc group received oral zinc supplementation; 2.5 ml every 12 hours for children aged <1 year and 5 ml every 12 hours for older children.
干预措施: Zinc Supplement, probiotic (Dietary Supplement)
65 children in Probiotic group
The probiotics group received oral probiotics; 1 probiotic sachet (KidiLact: Lacticaseibacillus rhamnosus, Lactobacillus reuteri, Lactobacillus acidophilus, Bifidobacterium infantis, Lactobacillus acidophilus, Bifidobacterium bifidum and Streptococcus thermophilus)
干预措施: Zinc Supplement, probiotic (Dietary Supplement)
结局指标
主要结局
Rate of Antibiotic-Associated Diarrhea
时间窗: 6 month
Passing loose, watery stools three or more times a day after taking antibiotic by questionnaire.
次要结局
未报告次要终点
研究者
Mohammad Bagher Rahmati
Hormozgan University of Medical Sciences
Hormozgan University of Medical Sciences