Comparative Study on the Value of Three DWI Scan Sequences of 3.0T Magnetic Resonance in Staging of Gastric Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 129
- 试验地点
- 1
- 主要终点
- T staging of gastric cancer
研究概览
简要总结
Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.
This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients.
A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The patient was diagnosed with gastric cancer by pathological biopsy
- •No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
- •No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.
排除标准
- •The image quality cannot meet the diagnostic criteria;
- •Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.
研究组 & 干预措施
SS-EPI-DWI T-stage of gastric cancer
TSE-DWI T-stage of gastric cancer
干预措施: Scanning parameter (Diagnostic Test)
ZOOM-DWI T-stage of gastric cancer
干预措施: Scanning parameter (Diagnostic Test)
结局指标
主要结局
T staging of gastric cancer
时间窗: one year
Study on the value of three DWI scanning sequences in T staging of gastric cancer
次要结局
未报告次要终点