Comparison of Small Colorectal Polyp Removal Using Cold Endoscopic Mucosal Resection With Hot Endoscopic Mucosal Resection: a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Complete removal of the colorectal polyp
研究概览
简要总结
This study evaluates the efficacy of small colorectal polyp removal using cold endoscopic mucosal resection with hot endoscopic mucosal resection. Half of the participants will receive cold endoscopic mucosal resection, while the other half will receive hot endoscopic mucosal resection.
详细描述
Colorectal polyps are considered as precancerous lesions and endoscopical resection is currently the treatment of choice when it is possible.
Colorectal polyps are classified into diminutive polyps (<5mm in diameter), small polyps (6-9mm in diameter), and large polyps (>1cm in diameter). There are several endoscopical treatment methods: cold biopsy forceps polypectomy, cold snare polypectomy, hot biopsy forceps polypectomy, hot snare polypectomy, and endoscopic mucosal resection. Cold polypectomy means mechanical removal of the polyp with snare or biopsy forceps without the use of electrocautery, and hot polypectomy means removal of the polyp with the use of electocautery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with colorectal polyps that are <1cm in diameter who need endoscopic mucosal resection.
- •Patients who gave informed consents to this study.
排除标准
- •Patients under the age of 19
- •Patients who are receiving antiplatelet or anticoagulant therapies
- •Patients with hypercoagulability (i.e., liver cirrhosis, hemophilia, end-stage renal disease, or chronic kidney disease)
研究组 & 干预措施
Cold EMR group
Patients who have small colorectal polyps (<1cm) who receive endoscopic mucosal resection using snare without electrocautery.
干预措施: Cold endoscopic mucosal resection (Procedure)
Hot EMR group
Patients who have small colorectal polyps (<1cm) who receive endoscopic mucosal resection using snare with the use of electrocautery.
干预措施: Hot endoscopic mucosal resection (Procedure)
结局指标
主要结局
Complete removal of the colorectal polyp
时间窗: At the time of the procedure (endoscopic mucosal resection)
The resected specimen will be reviewed microscopically to assess complete resection including the lateral and base margins
次要结局
- Procedure time(At the time of the procedure (endoscopic mucosal resection))
- Complication after endoscopic mucosal resection(Within 1 month)
研究者
Chang Hwan Park
Professor
Chonnam National University Hospital