NCT00978289已完成不适用
Microenvironment of Adipose Tissue in Endocannabinoid System Before and After Roux-en-y Gastric Bypass Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is examine the relationship between adipose tissue inflammation and activation of the endocannabinoid system before and after Roux-en-Y gastric bypass surgery. The investigators hypothesize that the metabolic improvements and weight loss are due to mechanisms that antagonize the endocannabinoid system.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI>35 kg/m2
- •Age 20-60 yrs
- •Approved and scheduled for gastric bypass surgery
- •Stable body weight for past 3 months
排除标准
- •Positive pregnancy test
- •Previous gastric surgeries
- •Intercurrent infections
- •History of ketoacidosis or current metabolic acidosis
- •Serum creatinine or liver function tests > 2 times upper limits of normal
- •Taking drugs that are known to affect carbohydrate or lipid metabolism other than anti-diabetes mediations.
研究者
Naji Abumrad
Chairman, Department of Surgery
Vanderbilt University
研究点 (1)
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