临床试验/NCT00899405

NCT00899405招募中不适用

EGFR Pathway Mutations in Lung Cancer Patient Tumors and Blood

University of California, Davis2 个研究点分布在 1 个国家目标入组 800 人开始时间: 2004年5月19日最近更新: 2026年6月25日

适应症

试验速览

阶段: 不适用
状态: 招募中
发起方: University of California, Davis
入组人数: 800
试验地点: 2
主要终点: Mutational status of the EGFR pathway

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This laboratory study is looking at tumor tissue samples and blood samples to learn more about DNA changes in patients with lung cancer.

详细描述

OBJECTIVES:

Examine the mutational status of the EGFR pathway in tumor and blood samples from patients with lung cancer.
Correlate the EGFR pathway mutations in these samples with clinical outcomes of these patients.

OUTLINE: Archived tumor tissue and blood samples are analyzed via PCR to detect EGFR pathway mutations in DNA.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•DISEASE CHARACTERISTICS:
•Histologically or cytologically confirmed lung cancer
•PATIENT CHARACTERISTICS:
•Not specified
•PRIOR CONCURRENT THERAPY:
•May have received prior EGFR inhibitors

排除标准

未提供

结局指标

主要结局

Mutational status of the EGFR pathway

时间窗: up to 1 year

次要结局

未报告次要终点

研究者

发起方

University of California, Davis

申办方类型

Other

责任方

Sponsor

研究点 (2)

Loading locations...

相似试验

Unknown

不适用

Human EGFR Mutations Quantitative Detection Kit (Real-time Fluorescent PCR Method)Non Small Cell Lung CancerEGFR-TKI Resistant MutationEGFR-TKI Sensitizing Mutation

NCT02661009GenoSaber1,000

撤回

不适用

Laboratory Study Using Samples From Patients With Non-Small Cell Lung Cancer Treated on Clinical Trial CASE-2507Lung Cancer

NCT00907699Case Comprehensive Cancer Center

已完成

不适用

Epidermal Growth Factor Receptor and K-ras Mutations in Patients With Stage III Non-Small Cell Lung CancerLung Cancer

NCT00898924Alliance for Clinical Trials in Oncology60

已完成

不适用

Monitoring study of genomic mutations in patients with EGFR mutation or ALK translocation using plasma DNAnon-small-cell lung cancer

JPRN-UMIN000035628Wakayama Medical University100

招募中

不适用

DNA Analysis of Blood and Tissue from Patients with Lung CancerLung Cancer

NCT00471978Massachusetts General Hospital6,800