JPRN-UMIN000053659已完成Unknown
Prospective observational study to analyze the association between the pathogenesis of perforated peptic ulcers and HLA. - Prospective observational study to analyze the association between the pathogenesis of perforated peptic ulcers and HLA.
Study Group for Gastroenterological Disease0 个研究点目标入组 422 人开始时间: 2024年2月26日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 422
研究概览
简要总结
- Patients with (n = 303) and without (n = 119) PPU recruited from our member hospitals and more likely to have duodenal ulcers, young, consume alcohol, and smoke. There was no significant difference in sex and ulcer recurrence. Perforated peptic ulcer patients and patients who underwent vagotomy decreased risks of cancer development. 2. Patients harboring HLA-Cw1 and -Cw7 and their heterozygotes protected against PPU development, whereas HLA-Cw3 reduced cancer development.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- 未提供
研究者
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