Impact of Haskap Berries on Recovery From High Intensity Resistance Training
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Force Production
研究概览
简要总结
The purpose of this clinical trial is to determine how certain food items affect oxidative stress, inflammation, and performance recovery from exercise induced muscle damage in a resistance trained population. The main questions The investigators aim to answer are the following:
- Do Haskaps speed the recovery of oxidative stress and inflammation markers after an intense lower body workout in resistance trained adults?
- Do Haskaps speed the recovery of performance measures after an intense lower body workout in resistance trained adults?
- The data collected in this investigation may also be used to ask additional questions not yet identified. For example, the investigators may use the stored samples to evaluate how the blood metabolites of participants differ before and after intense exercise. These additional questions are called secondary analyses. Please note that no genetic analysis will be conducted and racial and ethnic differences among participants will not be used in any secondary analyses.
Researches will compare Haskap juice to a color, flavor and carbohydrate matched placebo to see if Haskaps speed recovery in inflammation, oxidative stress and performance.
- Participants will be asked to drink either Haskap juice or placebo and follow a low polyphenolic diet
- Participants will perform an intense resistance workout
- Participants will have their blood drawn before and after the workout
- Performance will be analyzed at 24, 48 and 72 hours after the workout
详细描述
The main goal of the clinical trial is to learn more about how the haskap berry impacts the recovery process form intense resistance training. Haskap berries are very high in several compounds that function as antioxidants, such as polyphenols and vitamin C, which have many health promoting effects. For example, antioxidants lower inflammation and oxidative stress, which is known to cause damage to cells, proteins, and DNA. Oxidative stress is a result of excess free radicals, which are unstable molecules that can be created, along with inflammation, during intense exercise. This combination of excessive harmful byproducts in the body can cause soreness and decrease muscle performance experienced after a workout. However, the antioxidants in foods have the ability to neutralize free radicals that are produced and may reduce the time to recover from exercise.
To do this, a parallel, randomized, double blind, placebo controlled clinical trial of Haskap versus a placebo on resistance trained individuals will be completed. Participants will complete an intense workout consisting of barbell back squats and leg extension. Participants will drink either Haskap juice or placebo and follow a low polyphenolic diet for a total of 11 days. Participants will have their blood drawn before supplementation, before, immediately after and 8, 24, 48, and 72 hours after the workout to track recovery of blood markers. Performance will be analyzed via vertical jumps on force plates, maximal voluntary contraction of the quadriceps on a biodex, and speed of the squat at 24, 48, and 72 hours post workout.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Investigator)
盲法说明
Placebo and haskap interventions were designed to be comparable in taste, carbohydrate content, and appearance.
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •2+ years of barbell squat experience
- •Currently squatting at least once a week
排除标准
- •BMI <18 or > 40 kg/m^2
- •potential allergy to Haskap or placebo ingredients
- •anti-inflammatory, weight loss, anabolic steroids, testosterone, or other drugs that may interfere with the measures of the study or any other medications that may interfere with study measures
- •pregnant or lactating woman
- •diagnosis with type 1 or type 2 diabetes, hypo-/hyperthyroidism or any other condition that may interfere with study measures
- •smoke cigarettes
- •lower extremity injury within the last year
- •currently following a special diet including vegan, vegetarian, low carbohydrate, or ketogenic.
- •currently consuming any of the following products: tart cherry juice, pomegranate juice, or 1 or more cups of acai or other berries per day.
研究组 & 干预措施
Placebo Control
The placebo supplement will have no polyphenol content and will be carbohydrate-matched to the experimental group. A twice daily dose (10-12 hours apart) will be consumed for 11 days.
干预措施: Placebo Comparator (Dietary Supplement)
Haskap
The haskap supplement will consist of a haskap berry smoothie. A twice daily dose (10-12) hours apart will be consumed for 11 days.
干预措施: Haskap berry smoothie (Dietary Supplement)
结局指标
主要结局
Force Production
时间窗: 72 hours
Maximal Voluntary Contraction (MVC) to assess force production of knee extensors at 60 degrees.
Barbell Velocity
时间窗: 72 hours
Barbell velocity will be measure to determine how squat velocity recovers over the course of the study.
Vertical Jump
时间窗: 72 hours
Force plates will be used to evaluate vertical jump height.
Inflammation (pg/mL)
时间窗: 11 days
Serum interleukin (IL) IL-6, IL-10, IL-1ra, tumor necrosis factor alpha (TNF-alpha),
Lipid peroxidation
时间窗: 11 days
Plasma Malondialdehyde (MDA)
Creatine Kinase
时间窗: 11 days
Plasma
C-Reactive Protein
时间窗: 11 days
Plasma
Protein Carbonyls
时间窗: 11 days
Plasma
次要结局
- Soreness(72 hours)
- Acute Diet(9 days)
- Sleep questionnaire(11 days)