Individual Differences in Alcohol Sensitivity
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
研究概览
简要总结
This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80. Participants will complete two sessions during which they will complete questionnaires and laboratory measures of mental abilities and brain activity and receive a beverage that may or may not contain a moderate dose of alcohol.
详细描述
As a preliminary, proof-of-concept study, the project is designed to provide information regarding variability in response to a moderate dose of alcohol among healthy men and women who are current drinkers and aged 65 to 80. It is expected that approximately 75 individuals will complete the study. Participants complete two laboratory sessions. Each session will include consuming a beverage that may or may not include alcohol. If the beverage does include alcohol, the volume will not exceed the amount that a drinker might consume in 1 to 2 drinks. The outcomes will provide information regarding the how older adults vary in their response to alcohol and explore whether alcohol sensitivity is related to selected measures of cognition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 80 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Alcohol Drinkers who consume alcohol on a regular basis
- •No history of significant substance misuse
- •at least 12 years of education or GED equivalence
排除标准
- •current Cigarette smoker
- •Type 1 Diabetes or uncontrolled Type 2 Diabetes
- •Neurodegenerative disorder
- •Significant psychiatric disorder such as a psychotic disorder, bipolar disorder, current major depression or PTSD