Effect of Whey Protein Hydrolysate on Adaptions to Endurance Training in Well-trained Runners
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 4
- 主要终点
- Maximal oxygen uptake
研究概览
简要总结
Twenty-four well trained runners (VO2max 60.73.7 ml O2 Kg-1 min1) completed a six week block randomized controlled intervention period. Subjects were randomly assigned to either PRO-CHO or CHO and matched in pairs for gender, age, VO2max, training and performance status. The PRO- CHO group ingested a protein beverage (0.3g kg-1) before and protein-carbohydrate beverage (0.3g protein kg-1 and 0.1g carbohydrate kg-1) after each exercise session. The CHO group ingested energy matched carbohydrate. Post-absorptive muscle biopsies were obtained pre and post intervention for analysis HAD, CS and PGC-1. Subjects completed two physical tests 6 km performance test (pre, week 1 and week 6) and aVo2max test (pre and post intervention).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
盲法说明
Single blinded
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •maximal oxygen uptake (VO2max) of >50ml O2 kg-1 min-1 for women and >55ml O2 kg-1 min-1 for men,
- •running at least 3 times a week and
- •running being the primarily training form
排除标准
- •use of medicine
- •diagnosed metabolic diseases
- •injuries which hindered running and body mass index (BMI) < 25 kg m-2
结局指标
主要结局
Maximal oxygen uptake
时间窗: Change from week 1 to week 6
maximal oxygen uptake (L O2/min)
次要结局
- COX-IV(Change from week 1 to week 6)
- VDAC(Change from week 1 to week 6)
- CytC(Change from week 1 to week 6)
- HSP60(Change from week 1 to week 6)
- CD36(Change from week 1 to week 6)
- Performance(Change from week 1 to week 6)
研究者
Mette Hansen
Principal investigator
University of Aarhus