Uterine Artery Doppler and Three Dimensional Power Doppler in the Diagnosis of Myometrial Masses
试验速览
- 阶段
- 2 期
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Uterine artery doppler indices in fibroids in relation to adenomyosis
研究概览
简要总结
Colour Doppler sonography has also been evaluated in differentiating adenomyosis from fibroids. Two dimensional color Doppler ultrasound revealed that 87% of adenomyosis cases had vessel distributions different from those found in leiomyoma cases, in addition to a high pulsatility index (PI) .Adenomyotic lesions had randomly scattered vessels or intratumoral signals while leiomyomas usually had peripheral scattered or outer feeding vessels.
详细描述
Because it is more sensitive, less angle-dependent, and not susceptible to aliasing , power Doppler Sonography has the potential to detect fluctuations in blood flow , with results superior to those of frequency-based color Doppler sonography, particularly in situations of low-velocity blood flow. Three dimensional power Doppler ultrasonography can be applied to differentiate between uterine adenomyosis and leiomyoma ,and it may reduce the number of false positives by detailed investigations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age between 20 & 60 years.
- •Asymptomatic pts which discover the mass accidentally .
- •Patients with symptoms like menorrhagia, menometrorrhagia, dysmenorrheal , abdominal masses.
- •Patients scheduled for hysterectomy(abdominal/vaginal or Laparoscopic)
- •Patients scheduled for myomectomy.
排除标准
- •Pregnant patients
- •Age over 60 or under 20years.
- •Conservative management (Non surgical)
研究组 & 干预措施
myometrial fibroid/adenomyoma
Patients scheduled for myomectomy or hysterectomy with preoperative diagnosis of uterine myoma, adenomyosis or both by ultrasound .Trans-vaginal 3D power Doppler and uterine artery doppler will be done for all participants prior to surgery.
干预措施: Three dimensional Power Doppler to the myometrial mass (Other)
myometrial fibroid/adenomyoma
Patients scheduled for myomectomy or hysterectomy with preoperative diagnosis of uterine myoma, adenomyosis or both by ultrasound .Trans-vaginal 3D power Doppler and uterine artery doppler will be done for all participants prior to surgery.
干预措施: Uterine artery Doppler (Other)
结局指标
主要结局
Uterine artery doppler indices in fibroids in relation to adenomyosis
时间窗: 9 months
Uterine artery doppler indices(RI,PI) in fibroids in relation to adenomyosis
Power Doppler Vascular indices
时间窗: 9 months
The ultrasonographic examination will provide data related to lesion size, lesion volume, uterine artery doppler indices and vascular location (location), vascular index (VI), flow index (FI), and vascular-flow index (VFI). The region of interest will include the entire region of the uterine mass. The virtual organ computer aided analysis (VOCAL) software for the analysis of 3D power Doppler histograms will be used with computer algorithms to form indices of blood flow and vascularization. All data will be collected and compared with the post operative histopathology results.
次要结局
未报告次要终点