ACTRN12609001041246已完成4 期
In women receiving spinal anaesthesia for caesarean section, is there a difference in the opioid dose-sparing, analgesic efficacy and quality of post-operative pain relief provided by multimodal postoperative analgesic regimens based on patient controlled epidural analgesia (PCEA) with pethidine, together with either placebo, cyclo-oxygenase 2 enzyme (COX-2) inhibitors, paracetamol or COX-2 inhibitors and paracetamol in combination.
King Edward Memorial Hospital for Women0 个研究点目标入组 120 人开始时间: 2009年12月4日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- Female
入选标准
- •Elective caesarean section under combined spinal epidural anaesthesia
- •American Society of Anesthesiologists classification 1 or 2
排除标准
- •Pre-operative use of opioid medication
- •Contraindication to combined spinal epidural anaesthesia
- •Contraindication to parecoxib, celecoxib, paracetamol or tramadol
- •Known intolerance or allergy to oxycodone, morphine, parecoxib, celecoxib or sulphonamides
- •Pre-operative pruritus or nausea
- •Failure to identify the subarachnoid space or to catheterise the epidural space at the time of combined spinal epidural anaesthesia
- •Inadvertent dural puncture with the epidural needle or catheter
- •Requirement for intra-operative opioid or epidural analgesics other than local anaesthetic
- •Conversion to general anaesthesia
研究者
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