Using tDCS in Speech-based Stroke Rehabilitation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 24
- 试验地点
- 4
- 主要终点
- Change in accuracy in recordings from tasks from baseline to post treatment
研究概览
简要总结
The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation. Transcranial direct current stimulation (tDCS), which delivers low-intensity current to the scalp, and is a safe and well-tolerated approach that poses a non-significant risk to participants. tDCS provides low intensity neural stimulation which has been shown to facilitate motor learning in other domains of stroke rehabilitation such as arm motor learning but the potential to enhance speech motor learning has not been explored. This will be examined with a series of single-case experimental designs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Right-handed
- •Monolingual (English)
- •Single left-hemisphere CVA
- •A minimum of six months post-stroke
- •Clinical diagnosis of apraxia of speech
- •Normal speech perception
- •Passing score on the hearing screening.
排除标准
- •Diagnosis of laryngeal voice disorder
- •Dysarthria
- •History of speech impairment prior to CVA
- •Presence of potential tDCS risk factors: damaged skin at site of stimulation;
- •Presence of electrically or magnetically activated implant (including pacemaker);
- •metal in any part of their body;
- •history of medication-resistant epilepsy in the family;
- •past history of seizures or unexplained spells of loss of consciousness.
研究组 & 干预措施
Active Stimulation
crossover design such that each participant receives behavioral treatment twice - once with active stimulation and once with sham stimulation - in order to evaluate differences in improvement based on treatment condition.
干预措施: Sham (Device)
Active Stimulation
crossover design such that each participant receives behavioral treatment twice - once with active stimulation and once with sham stimulation - in order to evaluate differences in improvement based on treatment condition.
干预措施: Soterix 1x1 line tDCS low-intensity stimulator (Device)
Sham Stimulation
crossover design such that each participant receives behavioral treatment twice - once with active stimulation and once with sham stimulation - in order to evaluate differences in improvement based on treatment condition.
干预措施: Soterix 1x1 line tDCS low-intensity stimulator (Device)
Sham Stimulation
crossover design such that each participant receives behavioral treatment twice - once with active stimulation and once with sham stimulation - in order to evaluate differences in improvement based on treatment condition.
干预措施: Sham (Device)
结局指标
主要结局
Change in accuracy in recordings from tasks from baseline to post treatment
时间窗: Baseline, 6 Months
Subjects will be given speech production tasks. Recordings of tasks will be scored for accuracy to measure speech motor learning
次要结局
未报告次要终点