A COMPARATIVE STUDY OF PREOPERATIVE VERSUS POSTOPERATIVE ADMINISTRATION OF 120 mg ETORICOXIBS IN MANDIBULAR THIRD MOLAR SURGERY: A RANDOMIZED SPLIT-MOUTH DOUBLE-BLINDED CLINICAL TRIA

Department of Oral and Maxillofacial Surgery, Floor 13, faculty of Dentistry, Mahidol university0 个研究点目标入组 31 人开始时间: 2021年7月26日最近更新: 2024年8月19日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 31

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

Preoperative administration of Etoricoxib 120 mg revealed significant average pain reduction when compared to the same amount of drug administered postoperatively after four hours of local anesthesia deposition in mandibular third molar surgery. The mean rescue analgesic requirement was not statistically significant between both groups in postoperative evaluation period.

研究设计

研究类型: Observational

入排标准

年龄范围: 18 Years 至 30 Years（—）
性别: All

入选标准

•1. American Society of Anesthesiologists ASA : class I or II
•2. Patients with presence of asymptomatic, bilaterally similar partially or totally impacted lower third molars as classified by the inclination according to the Winter classification, class and position according to the Pell and Gregory classification that requires flap opening, bone removal, and tooth separation during the operation
•3. Age 18 to 30 years

排除标准

•1. Patients with any history of allergy to non-steroidal anti-inflammatory drugs
•2. Presence of systemic disease that contraindicates the surgical procedure such as uncontrolled hypertension, uncontrolled diabetes, asthma, and any pathological disease
•3. Pre-existing acute infection and inflammation
•4. Patients with a history of narcotic or alcohol abuse
•5. Chronic opioid analgesic use
•6. Pregnancy and lactating mother
•7. The surgical time exceeding 120 minutes or any surgical complications occurred that would render the procedures non-comparable
•8. Unable to follow the instructions or refusal to the follow-up appointments

研究者

发起方

Department of Oral and Maxillofacial Surgery, Floor 13, faculty of Dentistry, Mahidol university

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终止

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