NCT04682340已完成不适用
Analysis of Bisphenol A Concentration in Serum in Women of Reproductive Age With Autoimmune Thyroid Disease
Jagiellonian University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2020年12月22日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Comparison of serum BPA levels between the group with AITD and control group
研究概览
简要总结
The aim of the study is to assess the relationship between the concentration of bisphenol A in serum and selected parameters of thyroid function in women of reproductive age with thyroid dysfunction - Hashimoto's disease and Graves' disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Graves' disease or Hashimoto's disease (positive thyroid autoantibody)
- •Control group: thyroid autoantibody negative, normal thyroid function
- •Women aged 18 to 45 in both the control group and experimental group
排除标准
- •Pregnancy and lactating women
- •Previous or planned treatment with 131I or thyroidectomy
- •The use of drugs affecting the thyroid function (lithium, amiodarone, interferon a, sodium nitroprusside, sunitinib, sorafenib, iodine contrast, antibiotics / antifungals / antivirals (for at least 4 weeks prior to recruitment to the study), which do not result from the treatment of thyroid disease (levothyroxine, thyreostatic drugs, glucocorticoids)
- •Active malignancy
- •Other autoimmune diseases
- •Other endocrine diseases
- •Patients with severe liver, kidney or heart failure
结局指标
主要结局
Comparison of serum BPA levels between the group with AITD and control group
时间窗: Dec 2020 - April 2021
次要结局
- The association between serum BPA levels and serum thyroid hormone levels in the AITD group(Dec 2020 - April 2021)
研究者
Karolina Zawadzka
Principal Investigator
Jagiellonian University
研究点 (1)
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