Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,584
- 试验地点
- 1
- 主要终点
- Hospital Length of Stay
研究概览
简要总结
Preliminary retrospective data suggest that the relatively soluble but inexpensive volatile anesthesia isoflurane prolongs the duration of hospitalization compared to the less soluble but more expensive anesthetic sevoflurane. Even a small reduction in the duration of hospitalization would easily compensate for the modest additional cost of sevoflurane. The investigators therefore propose to test the primary hypothesis that duration of hospitalization is longer with isoflurane than sevoflurane.
The investigators will also test the secondary hypotheses that: 1) pain scores are greater in patients recovering from isoflurane than sevoflurane anesthesia; and, 2) opioid consumption is greater after isoflurane than sevoflurane anesthesia. All statistical analyses will be adjusted for age, gender, race, baseline risk, 9 and procedure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Must have surgery in G operating room suite
排除标准
- 未提供
研究组 & 干预措施
Isoflurane
Isoflurane is to be administered to patients in this arm during surgery
干预措施: Isoflurane (Drug)
Sevoflurane
Sevoflurane is to be administered to patients in this arm during surgery
干预措施: Sevoflurane (Drug)
结局指标
主要结局
Hospital Length of Stay
时间窗: participants will be followed for the duration of hospital stay, an expected average of 3 days
次要结局
- Time-weighted Average Verbal Rating Pain Score(up to 72 hours after surgery)
- Total Intraoperative Opioid Consumption(intraoperative)
研究者
d sessler
Professor & Chair
The Cleveland Clinic