Profile Study of Genomics Endometrial Expression After Gonadotropin-releasing Hormone Agonist Administration and GnRH in Endometrial Priming.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 6
- 试验地点
- 2
- 主要终点
- genetic endometrial human profile expression
研究概览
简要总结
The aim of this study is to analyse genomics profile expression in endometrium under different endometrial priming for recipients.
详细描述
We analyze the genomic profile of egg donors in different endometrial priming protocols, compared with natural cycle, including the conventional single long acting GnRH agonist injection in the mid luteal phase of the previous cycle of the endometrial priming and the single daily antagonist injection (Cetrorelix 0.25 mg) administered in the early follicular phase followed by endometrial priming. Endometrial biopsy will be taken in luteinizing hormone
- 7 or with P4 +5 in cases with endometrial priming with oestrogens therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •6 egg healthy volunteer egg donors.
- •Volunteers.
- •18-35 years old
- •BMI <28.
排除标准
- •- BMI > 28
结局指标
主要结局
genetic endometrial human profile expression
时间窗: Oocyte donors will be followed up for four to six months
implantation related genes profile expression
次要结局
未报告次要终点
