Efficacy Of Krishnatiladi Kashyam Ghanvati As Artava Janan (Mensturation) In Patients Of Avrita Vata Artava Dushti WSR PCOS (Phenotype D)

Polycystic Ovarian Syndrome is a most common metabolic and endocrine disorder in women of reproductive age It affects an estimated 5 to13 percent females and up to 70 percent of women with PCOS worldwide remains undiagnosed  Symptoms of PCOS include Amenorrhea or infrequent menstruation irregular bleeding and infrequent or no ovulation and multiple immature follicles. Later complication of PCOS is associated with type 2 diabetes  heart disease and ovarian cyst. According to the Rotterdam consensus  PCOS is determined by the presence of at least two out of three of the following features: evidence of oligomenorrhea (cycles  greater than 35 days apart or less than 8 cycles per year) or anovulation or biochemical or clinical hyperandrogenism and Polycystic ovarian morphology  greater than or equal to 12 follicles measuring  two to nine  mm in diameter and or an ovarian volume greater than10 mL in at least one ovary) . Phenotype D  oligomenorrhoea / anovulation and PCOS without Clinical or biochemical hyperandrogenism. In Ayurvedic literature details as per PCOS is not described.  It is a syndrome involving Pitta and  Kapha  and Rasa dhatu Dushti Dhatwagni mandya and Artava Dushti.    It has been mentioned  in   Yogaratnakar Yonivyapchikitsa Adhyaya that after the use of decoction prepared from Krishna Tila (Sesame indicum Linn) Shelu (Cordia dichotoma Forst) and Karvi (Nigella sativa Linn) mensuration will start in three days. Krishna tila and Karvi is having Ushna Veerya these drug may initiate mensuration. So this study may evaluate the efficacy of KrishnaTiladikashayam  in dosage form of ghanvati  as artavajanan (emmenagogue). It may be more feasible dosage form for artavajanan on the PCOS (Phenotype D ) patients.