Dead Space Effect of an Anaesthesia Gas Reflector (AnaConDa)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Region Skane
- 入组人数
- 6
- 试验地点
- 2
- 主要终点
- Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas.
研究概览
简要总结
The anesthesia gas reflector (AnaConDa) is built on the adsorptive capacity of active carbon which also adsorbs carbon dioxide in exhaled air. Rebreathing of carbon dioxide thus occurs and must be compensated for by increased ventilation. This study aims at determining how much compensation must be given, based on the hypothesis that rebreathing depends on carbon dioxide level in blood and exhaled air.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •elective coronary artery by-pass graft surgery
- •elective valve replacement surgery
- •normal left ventricular ejection fraction on preoperative echocardiography
排除标准
- •obstructive lung disease
- •restrictive lung disease
结局指标
主要结局
Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas.
时间窗: 1 hour
A conventional heat and moisture exchanger used in a respiratory circuit during anasthesia was exchanged by an AnaConDa. The AnaConDa causes re-breathing of carbon dioxide which clinically is equivalent to an increased airway dead space. The total airway dead space effect of the AnaConDa, i.e. volume of the device plus rebreathing from the charcoal filter was measured using the Single Breath Test for carbon dioxide, as was airway deadspace of the conventional Heat and Moisture Exchanger. Airway dead space differences between devices was calculated by subtraction of volumes thus achieved. Difference= Airway dead space AnaConDa - Airway dead space conventional Heat and Moisture Exchanger.
次要结局
未报告次要终点