ACTRN12617000643370已完成未知
The influence of exercise intensity on the prevention of cognitive decline in older adults
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 108
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
入排标准
- 年龄范围
- 60 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Aged 60-80 years, cognitively healthy (i.e. no diagnosis of dementia), adequate visual and auditory acuity to complete neuropsychological testing, willingness to participate in entirety of study, willingness and ability to provide written informed consent, able to provide a letter from usual GP endorsing participants ability to partake in all aspects of the study.
排除标准
- •1.A diagnosis of AD or another neurodegenerative disease, or a score of less than 26 on the Mini Mental State Examination.
- •2.Presence of clinical depression as measured by a score of 6 or greater on the Geriatric Depression Scale (GDS) Short Form.
- •3.Inability to undertake cycling-based exercise due to neuromuscular and/or musculo-skeletal limitations.
- •4.Inability to obtain medical clearance to participate in the exercise program.
- •5.Lifetime history of schizophrenia, shizoaffective disorder, or bipolar disorder
- •6.Subjects with untreated obstructive sleep apnoea
- •7.History of electroconvulsive therapy or serious head injury resulting in a prolonged period of unconsciousness.
- •8.History of alcohol abuse or dependence within 2 years of screening
- •9.Participants with a history of cancer (other than skin or in situ prostate cancer) within the previous 5 years
- •10.Any significant systemic illness or unstable medical condition that could lead to difficulty complying with the protocol including: history of myocardial infarction in the past year or unstable or severe cardiovascular disease including angina or Congestive Heart, chronic renal failure, chronic hepatic disease, severe pulmonary disease, epilepsy etc.
- •11.Insulin-requiring diabetes or uncontrolled diabetes mellitus
- •12.Uncontrolled hypertension (systolic BP greater than 170 or diastolic BP greater than 100)
- •13.Participants in whom magnetic resonance imaging (MRI) is contraindicated including, but not limited to, those with a pacemaker, presence of metallic fragments near the eyes or spinal cord, or cochlear implant (Dental fillings do not present a risk for MRI).
研究者
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