Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- fasting blood glucose (FBG)
研究概览
简要总结
All OCTA data and biochemical indexes of diabetic patients were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.
详细描述
Diabetic patients at the Department of Ophthalmology of the Seventh Affiliated Hospital of Sun Yat-sen University were selected as research participants. All OCTA data and biochemical indexes were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of diabetes
排除标准
- •various other types of retinal and choroidal disease;
- •history of any intraocular surgery or treatment (including intravitreal injection, retinal photocoagulation etc.
- •with severe refractive medium opacity that could affect fundus examination.
结局指标
主要结局
fasting blood glucose (FBG)
时间窗: the time of the patient's first 1 day visit
biochemical indexes
OCTA data
时间窗: the time of the patient's first 1 day visit
An image of the 3mm×3mm and 6 mm×6 mm macular areas detected by OCTA were captured. Quantitative analysis of vascular density and perfusion density of superficial capillary plexus in the macular area were automatically calculated using built-in software on the device.
glycosylated hemoglobin (HbAlc)
时间窗: the time of the patient's first 1 day visit
biochemical indexes
次要结局
未报告次要终点
研究者
Mingzhe Cao
Attending ophthalmologist
The Seventh Affiliated Hospital of Sun Yat-sen University