Refractory In and Out of Hospital Cardiac Arrest Treated With Extracorporeal Membrane Oxygenation. Observational, Single Centre, Prospective Study.
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 28 days survival
研究概览
简要总结
Extracorporeal membrane oxygenation (ECMO) support has been suggested to improve the survival rate in patients with refractory cardiac arrest (CA). Recent studies have also highlighted the potential early application of this method in improving the prognosis of prolonged cardiac arrest both for in hospital CA (INHCA) and out of hospital CA (OHCA). The rationale for use of ECMO in these patients is to optimize early perfusion of vital organs, curing the cause of CA and waiting for the recovery of the injured myocardium. The investigators have created a flow-chart to decide which patients are eligible. The aims of this study are to evaluate if, with this flow-chart, the investigators are able to detect which patients have more probability of survival.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults 18-75 years old
- •In and out of hospital Witnessed Cardiac Arrest
- •No-flow time < 5 min. or VF,VT,TP as rhythm of presentation
- •Low-flow time < 45 min.
- •End Tidal CO2 > 10 after 20 min.of CPR
排除标准
- •Comorbidities such:
- •Terminal Malignancy
- •Aortic Dissection
- •Severe Cardiac Failure without transplant indication
- •Severe Aortic Valve Failure
- •Known Severe Peripheral arteriopathy
结局指标
主要结局
28 days survival
时间窗: 28 days
次要结局
- Neurologic recovery(28 days)
- Cardiac recovery(28 days)
- Six months survival with minimal neurologic impairment(180 days)