Interaction Between White Potato Consumption and Meal Timing on Glycemic Response, Subjective Appetite, and Energy Intake in Adults.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Glycemic Response (Acute Phase)
研究概览
简要总结
The purpose of this study is to evaluate the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. The investigators hypothesize that white potatoes will modulate glycemic response, enhance satiety, and mitigate subsequent meal consumption and overall food intake when compared with meals containing low glycemic carbohydrates. Furthermore, they anticipate that the timing of white potato consumption will yield differential effects, with breakfast consumption exerting a more pronounced impact on satiety and subsequent food intake reduction compared to dinner consumption.
详细描述
A randomized within-subject repeated measures experiment will be used to study the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. In Experiment 1, participants will consume, in a random order on separate mornings, one of six test meals consisting of an egg omelette and a test side of: (1) Oven-baked home fries, (2) Oven-baked white russet potatoes, (3) Deep-fried, quick serve fries, (4) Oven-baked fries, (5) Oven-baked cauliflower tots, or (6) no side. Acute glycemic response and subjective appetite will be measured at baseline and over 120-mins post treatment consumption. At 120-min, food intake will be evaluated via an ad libitum lunch. Rest of day food intake and glycemic response will be collected until the participant goes to bed. Blood glucose measurements will be collected using the Dexcom G7 continuous glucose monitoring system.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 - 65 years
- •within the healthy body weight range [body mass index (BMI) between 18.5 - 24.9 kg/m2].
排除标准
- •have a previous diagnosis of diabetes and gastrointestinal, liver or kidney disease;
- •have had a major medical or surgical event within the past 6 months;
- •have had any significant weight fluctuation in the past 6-months;
- •are taking medication that may influence dependent measures;
- •are or have been on a diet within the past 6 months;
- •skip breakfast or are unable to consume test treatment food.
结局指标
主要结局
Glycemic Response (Acute Phase)
时间窗: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
Blood glucose (mmol/L). Blood glucose concentrations will be measured using a Dexcom G7 CGM system.
Rest-of-day Blood Glucose
时间窗: Continuous measurements for 24 hours post-treatment consumption.
Blood glucose (mmol/L). Rest-of-day blood glucose concentrations will be determined using a Dexcom G7 CGM system.
Ad Libitum Food Intake
时间窗: At 120 minutes post-treatment consumption
Lunch pizza meal. Food intake will be determined by weighing the meal before and after serving. The net weight of the test meal will be converted to calories.
次要结局
- Subjective Appetite(Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).)
- Rest-of-day Food Intake(For the rest of the day following test session completion (1 day))
- Subjective Emotions(Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).)
研究者
Nick Bellissimo, PhD
Professor
Toronto Metropolitan University