Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 4,000
- 试验地点
- 3
- 主要终点
- Mortality (i.e. number of participants who are deceased during postoperative day 0 up to year 5)
研究概览
简要总结
This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure.
Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.
详细描述
This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. In addition, we also examine blood and urine biomarkers (proteins).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Undergoing heart surgery
- •Willing to provide consent
排除标准
- •Enrolled in a concurrent drug or device trial that precludes concurrent enrollment
结局指标
主要结局
Mortality (i.e. number of participants who are deceased during postoperative day 0 up to year 5)
时间窗: Day of procedure to year 5
Data will be collected from electronic medical records; data points to be collected for this measurement include serum creatinine.
次要结局
未报告次要终点
研究者
Jochen Daniel Muehlschlegel, MD
Professor
Johns Hopkins University