NCT04278911Unknown不适用
Effect of Cognitive Impairment (CI) on Prognosis in the Elderly Patients With Acute Coronary Syndrome (ACS)
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- MACE (major adverse cardiovascular events)
研究概览
简要总结
This study aims to investigate the incidence and characteristics of cognitive Impairment(CI) in the elderly patients with acute coronary syndrome (ACS), and to determine whether CI are predictive of the prognosis of major adverse cardiovascular events (MACE) and mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed ACS diagnosis （include unstable angina, ST-segment elevation myocardial infarction and Non ST-segment elevation myocardial infarction）
- •fulfilled MMSE or MoCA
- •patients agreed and provided informed consent
排除标准
- •Type 2 myocardial infarction and Acute nonischemic myocardial injury
- •past history of malignant tumors
- •Past history of stroke or dementia
- •Hepatic insufficiency (ALT>8ULN or ALT>3ULN and TBIL>2ULN)
- •Renal insufficiency (GFR<15 ml/min/1.73m2)
结局指标
主要结局
MACE (major adverse cardiovascular events)
时间窗: 12 months
Myocardial infarction, revascularization, stroke, cardiac death, all cause of death
次要结局
- Cognitive level decline(12 months)
研究者
Hongwei Li, MD
Prof.
Beijing Friendship Hospital
研究点 (1)
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