Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- number of alcoholic cirrhosis patients with presence of alcohol-related cognitive disorders
研究概览
简要总结
80% of patients with alcohol use disorders (AUD) present cognitive impairments, such as memory and executive functions. These disorders may have repercussions in addiction treatment by altering the patient's adherence to care. The level of impairment is dependent on the onset of addiction, and also the duration of abstinence.
A complete neuropsychological evaluation is necessary to highlight cognitive impairments. In practice, the evaluation of these disorders by practitioners, is done with the help of tools of screening like the MoCa (Montreal cognitive assesment) and the BEARNI (Brief evaluation of alcohol related neuropsychological impairment).
However, none of these tools have been evaluated in patients with alcoholic cirrhosis. Indeed, some studies have suggested that liver disorders including cirrhosis may be a factor aggravating cognitive disorders.
The purpose of this study is to evaluate the ability of the BEARNI tool to detect alcohol-related cognitive problems in patients with alcohol-related cirrhosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with cirrhosis
- •patients with cirrhosis diagnosed by clinical examination
- •patients with cirrhosis diagnosed by biological and / or morphological and / or noninvasive tests and / or liver biopsy
- •CHILD A, B or C
排除标准
- •hepatitis encephalopathy less than 6 months old
- •complicated cirrhosis with hepatocellular carcinoma
- •Acute alcoholic hepatitis
- •viral cirrhosis
结局指标
主要结局
number of alcoholic cirrhosis patients with presence of alcohol-related cognitive disorders
时间窗: day 1
the number of alcoholic cirrhosis patients with presence of alcohol-related cognitive disorders will be measured by using the BEARNI screening tool. BEARNI screening tool is Brief evaluation of alcohol related neuropsychological impairment.
次要结局
未报告次要终点