Radiographic and Histomorphometric Assessment of Microfragmented Adipose Tissue Loaded on Bovine Graft on Ridge Preservation Versus Bovine Graft Only for Subsequent Implant Placement in the Maxillary Posterior Region, a Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 22
- 主要终点
- Quantity of bone (vertical bone height)
研究概览
简要总结
Evaluation of maxillary alveolar ridge changes (bone quantity and quality as revealed by Radiographic and Histomorphometry) utilizing microfragmented adipose tissue loaded on bovine graft versus bovine graft only for maxillary posterior ridge preservation.
详细描述
All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on bovine graft will be utilized for the study group and bovine raft only for the control group.
After 6 months, patients will be evaluated histomorphometrically via core biopsy at the time of implant placement and radiographically via assessment of ridge height on CBCT.
Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height from base line (1week) to 6 months postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients requiring implant treatment after tooth extraction due to either unrestorable caries lesions or affected periodontium.
- •Age group: above 21 years
- •Remaining natural teeth have good periodontal tissue support and occlusion showed sufficient inter arch space for future prosthesis.
排除标准
- •General contraindications to implant surgery.
- •Subjected to irradiation in the head and neck area less than 1 year before implantation.
- •Poor oral hygiene and motivation.
- •Severe bruxism or clenching.
- •Systemic, immunologic, or debilitating diseases that could affect normal bone healing & local pathosis.
- •Treated or under treatment of intravenous amino bisphosphonates.
- •Active infection or severe inflammation in the area intended for implant placement.
- •Patients participating in other studies if the present protocol could not be properly followed.
- •Heavy smokers
结局指标
主要结局
Quantity of bone (vertical bone height)
时间窗: Quantity of bone (vertical bone height) by CBCT after 6 months
By CBCT
次要结局
- Quality of bone(Histological analysis (Core biopsy) Percentage of newly formed bone after 6 months)
研究者
Bashaer Maruf Jamaan Bayashot
principal investigator
Cairo University