Assessment of Dimensional Changes Following Grafting With Microfragmented Adipose Tissue Loaded on Allograft on Ridge Preservation Versus Allograft Only for Subsequent Implant Placement in the Maxillary Posterior Region, a Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Alveolar ridge hight (bone quantity )
研究概览
简要总结
Evaluation of maxillary alveolar ridge changes (bone quantity and quality as revealed by radiographic and Histomorphometry ) utilizing microfragmented adipose tissue loaded on allograft versus allograft only for maxillary posterior ridge preservation
详细描述
All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on allograft will be utilized for the study group and allograft only for the control group.
After 3-6 months, assessment of dimensional changes ( RG height & width) on CBCT is performed and Histomorphometry will be evaluated via core biopsy at the time of implant placement in both groups.
Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height and width from base line (1week) to 3-6 months postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients requiring implant treatment after tooth extraction due to either unrestorable caries lesions or affected periodontium.
- •Age group: above 18 years
- •Remaining natural teeth have good periodontal tissue support and occlusion showed sufficient inter arch space for future prosthesis.
排除标准
- •• General contraindications to implant surgery.
- •Subjected to irradiation in the head and neck area less than 1 year before implantation.
- •Poor oral hygiene and motivation.
- •Severe bruxism or clenching.
- •Systemic, immunologic or debilitating diseases that could affect normal bone healing & local pathosis.
- •Treated or under treatment of intravenous amino-bisphosphonates.
- •Active infection or severe inflammation in the area intended for implant placement.
- •Patients participating in other studies, if the present protocol could not be properly followed.
- •Heavy somkers
结局指标
主要结局
Alveolar ridge hight (bone quantity )
时间窗: Alveolar ridge hight (bone quantity ) by CBCT after 3-6 months
By CBCT
次要结局
- Alveolar ridge width.(Alveolar ridge width. by CBCT after 3-6 months)
研究者
Maha Omar Salem Alnahdi
principal investigator
Cairo University