IRCT20081208001497N8招募中3 期
Evaluation of the effect of melatonin on biomarkers of mitochondrial damage in patients with brain injury hospitalized in Alzahra hospital, Isfahan: A randomized placebo-controlled clinical trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Adult patients (age more than 18) who had traumatic brain injury included skull fracture, subdural hemorrhage, subarachnoid hemorrhage, brain contusion and laceration, intracerebral hemorrhage, intraventricular hemorrhage and traumatic axonal injury
- •Non-traumatic brain injury included strokes, infections, hypoxia and brain tumors
- •Admission within 72 hours after brain injury in intensive care unit or other wards such as neurology or neurosurgery
- •Healthy gastrointestinal tract (capable of oral ingestion or gavage of drug)
排除标准
- •Length of hospitalization less than 5 days in intensive care units or other wards
- •Hypersensitivity to melatonin
- •Hepatic failure (class C according to Child-pugh)
- •Renal failure (need dialysis)
- •Severe heart failure (Class 3 and 4 according to Newyork heart association)
- •Sepsis within first 5 days of admission
研究者
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