Ultrasonographic evaluation of Internal Jugular Vein collapsibility index and its association with post induction hypotension in patients undergoing Supratentorial craniotomy A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 73
- 试验地点
- 1
- 主要终点
- To evaluate whether internal jugular vein collapsibility index can predict post induction hypotension in Patients Undergoing Supratentorial Craniotomy
研究概览
简要总结
All the patients satisfying inclusion criteria will be evaluated at least one day prior to surgery . NPO will be explained and written informed consent will be taken . No sedative premedication will be given . On the day of surgery Iv cannulation will be performed and normal saline will be given at 10 ml/hr body weight duuring study period. Ultrasonographic measurements of IJV diameter will be taken at the level of thyroid cartilage with minimum pressure at supine and 10 degree trendelenberg position respectively . Collapsibility index will be calculated . Standard ASA monitoring and anaesthesia technique will be used in all patients. Intraarterial cannulation will be performed after applying local anaesthesia .Fentanyl 2 mcg/kg , Propofol 1.5 - 2 mg /kg . Intubation will be done with cuffed ETT of appropriate size after administration of Inj .Vecuronium 0.1 mg/kg to facilitate endotracheal intubation . Anaesthesia will be maintained in all cases using 40 percent oxygen in air , Sevoflurane . Ventilation will be controlled to maintain ETCO2 of 35 mmhg . Continuous IABP will be recorded at induction and 1,2,3,4,5,10,15,20 minutes post induction . Systolic blood pressure less than 80 or greater than 30 percent decrease from baseline will be defined as significant hypotension. Mephentermine 6 mg will be given if hypotension of SBP less than 80 mmHg occurs.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA I , II, III Glasgow Coma Score more than 12.
排除标准
- •Refusal to participate 2) Patients undergoing emergency craniotomies, craniotomy for vascular pathologies (Subarachnoid hemorrhage, intracranial hemorrhage, arteriovenous malformations) 3) Patients with significant hepatic, renal, cardiovascular disease, 4) Patients with morbid obesity and difficult intubation 5) Patients operated in sitting and prone position 6) Glasgow Coma score less than or equal to 12.
结局指标
主要结局
To evaluate whether internal jugular vein collapsibility index can predict post induction hypotension in Patients Undergoing Supratentorial Craniotomy
时间窗: collapsibity index is assessed preoperatively and compared with blood pressure measured at 10 mins
次要结局
- To correlate preoperative Internal Jugular Vein collapsibility index in supine & 10-degree Trendelenburg position with mean arterial pressure measured five minutes after induction(Mean arterial pressure measured at induction,1,2,3,4,5,10,15,20 minutes post induction)
- To compare the Internal Jugular Vein collapsibility index in 10-degree Trendelenburg position
研究者
Darson Pudhin
AIIMS RISHIKESH
