Association of Preoperative Inflammatory Biomarkers With Postoperative Nausea and Vomiting in Children Undergoing Orchiopexy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- Incidence of Postoperative Nausea and Vomiting (PONV)
研究概览
简要总结
Orchiopexy is a common surgical procedure for the treatment of cryptorchidism in the pediatric population, with a high incidence of postoperative nausea and vomiting (PONV).
Recent evidence suggests that systemic inflammation may contribute to PONV pathogenesis, and preoperative inflammatory biomarkers such as NLR, PLR, SII, MLR, and SIRI could serve as predictive indicators.
This prospective observational study aims to evaluate the relationship between these biomarkers and PONV incidence in children undergoing orchiopexy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged between 1 and 8 years
- •Patients with ASA physical status I-II
- •Patients scheduled for elective orchiopexy
- •Obtained written informed consent from parents/guardians
排除标准
- •Patients younger than 1 year or older than 8 years
- •Patients with ASA physical status III or higher
- •Presence of acute infection signs
- •History of previous nausea or vomiting
结局指标
主要结局
Incidence of Postoperative Nausea and Vomiting (PONV)
时间窗: Within 6 hours postoperatively
PONV will be assessed using a standardized nausea-vomiting scoring system by an anesthesiologist blinded to biomarker results.
次要结局
- Need for Antiemetic Treatment(Within 6 hours postoperatively)
研究者
Elif Sule Ozdemir
Principal İnvestigator
Ankara Etlik City Hospital