Hyperbaric Levobupivacaine for Spinal Anaesthesia
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 73
- 试验地点
- 1
- 主要终点
- degree of motor blockade
研究概览
简要总结
Spinal anaesthesia also called spinal block or sub-arachnoid block (SAB), is a form of regional anaesthesia involving injection of a local anaesthetic into the subarachnoid space, generally through a fine needle.
There is no generic hyperbaric form of levobupivacaine currently available so we aimed in this study that to find the appropriate concentration of the levobupivacaine which achieves unilateral spinal anesthesia. The potential benefits of this type of anesthesia are less motor blockade and urinary retention, decrease in hospital stay. Therefore, it seems to be suitable for outpatient anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Approval to participate in the study and spinal anesthesia
- •American society of anesthesia (ASA) I,II physical status
- •Scheduled for lower extremity surgery
排除标准
- •Refuse to participate in the study
- •American society of anesthesia (ASA)III, IV physical status
- •Hypersensitivity to local anesthetics
- •Emergency surgery
- •Chronic pain treatment
- •Peripheral neuropathy
- •Severe systemic disease
研究组 & 干预措施
levobupivacaine I
group that was administered levobupivacaine plus 60mg dextrose
干预措施: levobupivacaine (Drug)
levobupivacaine II
group that was administered levobupivacaine plus 80 mg dextrose
干预措施: levobupivacaine (Drug)
levobupivacaine III
group that was administered levobupivacaine plus 100 mg dextrose
干预措施: levobupivacaine (Drug)
结局指标
主要结局
degree of motor blockade
时间窗: until dissolve of motor blockade
次要结局
未报告次要终点
研究者
özgür yağan
Özgür Yağan
T.C. ORDU ÜNİVERSİTESİ