Pulmonary Function Testing in Infants With Respiratory Insufficiency While Receiving High Flow Nasal Cannula (HFNC) Versus Nasal Continuous Positive Airway Pressure (nCPAP)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- lung compliance
研究概览
简要总结
The purpose of this study is to compare two common methods of providing respiratory support: nasal continuous airway pressure and high flow nasal cannula to see what effect it has on babies breathing. The investigators also will compare the effects of slightly changing the level of support these two different types of therapy on how easily your baby is breathing. Changes in the level of support and between these two respiratory support modalities are frequently done and are part of the routine care in the neonatal intensive care unit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 2 Days 至 6 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •* Infants who are between 28 and 40 weeks of corrected gestational age at the time of study entry
- •* Currently on high flow nasal cannula receiving 3 to 5 lpm or on nasal continuous positive airway pressure at 5 to 6 cmH2P with and FiO2 requirement \/= 12 hours and have been extubated from a mechanical ventilator for \>/= 48 hours.
排除标准
- •Infants with skeletal or neuromuscular disorders that affect the accuracy of RIP PFT measurements.
研究组 & 干预措施
HFNC to NCPAP
Infants who are currently on HFNC.
干预措施: Pulmonary function testing and esophageal pressure (Other)
NCPAP to HFNC
Infants who are currently on NCPAP.
干预措施: Pulmonary Function Testing & esophageal pressure monitoring (Other)
结局指标
主要结局
lung compliance
时间窗: 2 hours
Is there a difference in pulmonary function tests in infants with respiratory insufficiency being treated with high flow nasal cannula (HFNC) or nasal continuous positive airway pressure (NCPAP)?
次要结局
未报告次要终点